Overview:

Since 2013, AbbVie has expanded its commitment to the San Francisco Bay Area with the consolidation of three Bay Area facilities to a new Bay Area headquarters in South San Francisco. AbbVie employees in the Bay Area drive AbbVie’s research-based, innovation driven missions in healthcare. Specifically, Bay Area employees bring deep scientific expertise and commercial excellence to advance cancer care. Current oncology areas of focus include immuno-oncology, tumor targeting, tumor dependency and precision medicine. With facilities positioned in the heart of the biotechnology industry, we are able to collaborate with the best and brightest minds in oncology.

We have an exciting opportunity available for a Senior Scientist II within the Pharmaceutical Development Group in the AbbVie Bay Area (ABA) CMC Biologics department in South San Francisco, CA.

Key Responsibilities Include:

• Develop formulation and drug product manufacturing processes for ultra-low protein concentration products and complex biologics spanning multiple therapeutic areas in various phases of development.
• Drive technical innovation and fundamental scientific understanding of protein physiochemical degradation pathways; evaluate and recommend new approaches to inhibit protein adsorption/interfacial instability.
• Generate high-quality data based on sound scientific principles and prepare formulation data summaries, technical reports, scientific presentations, and regulatory documents.
• Raise the external influence of Abbvie in the scientific community through external presentations, patent applications, and publications.
• Actively participate in drug product development teams and contribute to the planning and execution of formulation and drug product process studies to meet project deliverables.
• Lead AbbVie global drug product initiatives and manage direct reports.
• South San Francisco-based position with 10-20% business travel.

Qualifications:

• Ph.D. in pharmaceutical sciences, chemistry, biochemistry, chemical engineering, analytical sciences, or equivalent field with 4+ years of experience or BS/MS degree with 10-12 years of relevant experience in the biotechnology or pharmaceutical industry.
• A strong technical background encompassing protein chemistry, protein physics, analytical development, and formulation development is required.
• Candidates must have hands-on expertise in analytical techniques used for protein characterization and stability testing.
• Prior experience in the development of complex protein product formulations, lyophilization process development, and fill-finish process is required. Late-stage and ultra-low dose product development experience is highly desirable.
• Prior experience demonstrating independent critical thinking for technical problem-solving and driving fundamental science through innovative science is highly desirable.
• Demonstrated ability to collaborate and influence cross-functional team initiatives while working in a matrixed environment is highly desirable.
• A track record of driving innovation, publication, and engagement with the external scientific community is highly desirable.
• Excellent communication and written skills are required.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.

We offer a comprehensive package of benefits including paid time off. (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees

This job is eligible to participate in our short-term incentive programs.

The salary range is (minimum: $96,000 to maximum:$188,000)

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer including disability/vets. It is AbbVie’s policy to employ qualified persons of the greatest ability without discrimination against any employee or applicant for employment because of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information, gender identity or expression, sexual orientation, marital status, status as a disabled veteran, recently separated veteran, Armed Forces service medal veteran or active duty wartime or campaign badge veteran or a person’s relationship or association with a protected veteran, including spouses and other family members, or any other protected group status. We will take affirmative action to employ and advance in employment qualified minorities, women, individuals with a disability, disabled veterans, recently separated veterans, Armed Forces service medal veterans or active-duty wartime or campaign badge veterans. The Affirmative Action Plan is available for viewing in the Human Resources office during regular business hours.