Job description

Senior Science Officer, Therapeutics
Development

Background

The California Institute for Regenerative Medicine (CIRM) is the state’s Stem Cell
Agency. We were created by the voters of California when they approved
Proposition 71 in 2004, and renewed when Proposition 14 was approved in 2020, providing $5.5 billion to invest in stem cell research in California. CIRM’s mission, to accelerate stem cell and regenerative medicine treatments to patients with unmet medical needs, is what drives us to succeed every day.

To meet this challenge, our team of highly trained and experienced professionals actively partners with both academia and industry in a hands-on, entrepreneurial environment to fast-track the development of today’s most promising stem cell and regenerative medicine technologies.

CIRM is the world’s largest institution dedicated to helping people by bringing the promise of regenerative medicine closer to reality.

General Statement
The mission of the Therapeutics Development team is to attract and advance the most promising stem cell-based technologies in cancer, in eye diseases and diseases of the nervous system, and in metabolic, vascular, and other organ system-related conditions (e.g., musculoskeletal, respiratory, liver, cardiovascular). Projects in the therapeutic areas range from translational research through human clinical trials.

Job Functions

Building the Portfolio

• Being up to date on trends and key developments in the stem cell and gene therapy research field.
• Works in a team environment in identifying and advancing the most promising translational and clinical stage stem cell-based and gene therapy technologies for unmet medical needs. Staying current and open-minded in ensuring only the most promising and well-constructed projects are considered for inclusion into the Therapeutics Development portfolio by supporting a highly competitive, fair, and rigorous peer review process.

Advancing the Portfolio

• Accelerates the development of promising projects by working in a collaborative and hands-on fashion with internal and external partners.
• Proactively identifies risks or deficiencies with active projects and leveraging internal and external resources to find solutions that provide the project with the greatest opportunity for success.
• Seeks new and innovative ways to improve and accelerate the therapies into the clinic.

Managing the Portfolio

• Assesses the progress of projects through objective metrics and ensuring the complete and up-to-date reporting on all projects in your portfolio.
• Works with the project teams to facilitate success.
• Monitors funding and other resources to ensure they are being used appropriately and efficiently.
• Recommends appropriate action to suspend or discontinue projects when warranted.

Communicating the Portfolio

• Represents CIRM and the Therapeutics Development at appropriate scientific, medical, governmental agency, and industry meetings and events.
• Provides clear and timely updates to CIRM leadership on the status of the portfolio.
• Engages with all stakeholders (scientific thought leaders, subject matter experts, patient advocacy groups) to build support for and advance projects.

Harmonizing with the CIRM Mission

• Demonstrate in your words and actions commitment to CIRM’s mission.
• Collaborates with others to generate efficiencies, enhance productivity, and develop competencies.
• Commits to team decisions by supporting and working to achieve team objectives.

Supervision Received
The Senior Science Officer reports to the Associate Director,Therapeutics
Development.

Qualifications and Skills
The Senior Science Officer will have scientific and clinical expertise and experience in cell/molecular biology, or a related discipline especially as applied to stem cells and gene therapy. Industry experience and familiarity with regulatory requirements related to cell and gene therapy early and late clinical development. The Senior
Science Officer will have an innate sense of urgency and determination to deliver outstanding results and to find innovative ways of meaningfully advancing CIRM’s mission.

• An “all in” commitment to accomplishing the mission of CIRM.
• Doctorate (MD/-,PhD, PharmD) in medicine, clinical research in the cell and gene therapy area,
• A minimum of 7 years of relevant experience beyond doctoral degree in biologic/drug development, Clinical & regulatory development, pharmaceutical

/biotechnology industry, and/or biomedical clinical research.

• Expertise in one of the therapeutic areas such as neurology, ophthalmology, hematology/oncology, or organ systems (cardiology, vascular, liver, or renal) is a plus.
• Knowledge and hands on experience with cell and gene therapy development process or related discipline that has a direct bearing on the clinical development of stem cell-based and gene therapies
• Ability to effectively manage, organize and prioritize multiple projects and meet deadlines in a fast-paced and demanding environment.
• Outstanding communication and interpersonal skills.
• Ability to make clear, concise, and impactful presentations.
• Ability to work collaboratively in a team-oriented environment.

Preferred Skills

• Experience with clinical project management and regulatory filings or interactions

(FDA, pre-IND, and IND filings).

Working Conditions

• Ability to operate standard office equipment.

During the COVID pandemic, remote work is acceptable, however eventual willingness to work collocated with the team is a must.

Attendance

Must maintain regular and acceptable attendance at such level as is determined at the Department’s sole discretion. Must be regularly available and willing to work the hours the Department determines are necessary or desirable to meet its business needs.

Salary Range and Benefits

The annual salary range for the Senior Science Officer position is $145,491 to
$228,273.

CIRM offers a competitive compensation and benefits package.

How to apply
Interested candidates please submit:

• Cover letter
• CV/Resume
• California State application at http://jobs.ca.gov/pdf/std678.pdf

**A California State application is required as CIRM is a state agency. You will not be considered without this.

To: jobscirm.ca.gov (Electronic applications preferred)
CIRM is an Equal Opportunity Employer and committed to a diverse workforce.

Dates printed on Mobile Bar Codes, such as the Quick Response (QR) Codes available at the USPS, are not considered Postmark dates for the purpose of determining timely filing of an application.

Address for Mailing Application Packages
You may submit your application and any applicable or required documents to:

Human Resources
Attn: CIRM, Jobs
P.O. Box 980790,
West Sacramento, CA 95798-0790

Required Application Package Documents
The following items are required to be submitted with your application. Applicants who do not submit the required items timely may not be considered for this job:

• Current version of the State Examination/Employment Application STD Form

678 form. All Experience and Education relating to the qualifications listed for this position should be included to demonstrate how you meet the essential functions of the job.

• Resume/CV
• Cover Letter

Application Information
All applicable fields on the State Examination/Employment Application (STD. 678) form must be filled out completely. Resume must be included. Clearly indicate on the STD.
678 form in the field titled “Examination(s) or Job Titles for Which You Are Applying” the position title as indicated on this job announcement. Employment history on your application must be complete with dates, description of duties and responsibilities for each position held, contact names and phone numbers of supervisors. Applicants who do not submit all the required documentation (incomplete application package) may be eliminated from the selection process.
NOTE: For security purposes, your full social security number is not required on the application.

For any inquiries about the position sent to jobscirm.ca.gov, the e-mail should have the position title on the subject line.

Contact Information
The Human Resources Manager is available to answer questions regarding the application process and the position.

Human Resources Contact:
Vanessa Singh
Email - jobscirm.ca.gov

Applicants requiring reasonable accommodations for the hiring interview process must request the necessary accommodations if scheduled for a hiring interview. The request should be made at the time of contact to schedule the interview. Questions regarding reasonable accommodations may be directed to the Equal Employment Officer listed below:

• Vanessa Singh
• Email: jobscirm.ca.gov
• California Relay Service: 1-800-735-2929 (TTY), 1-800-735-2922 (Voice) TTY is a

Telecommunications Device for the Deaf and is reachable only from phones equipped with a TTY Device.

Equal Opportunity Employer
The State of California is an equal opportunity employer to all, regardless of age, ancestry, color, disability (mental and physical), exercising the right to family care and medical leave, gender, gender expression, gender identity, genetic information, marital status, medical condition, military or veteran status, national origin, political affiliation, race, religious creed, sex (includes pregnancy, childbirth, breastfeeding, and related medical conditions), and sexual orientation.

It is an objective of the State of California to achieve a drug-free workplace. Any applicant for state employment will be expected to behave in accordance with this objective because the use of illegal drugs is inconsistent with the law of the State, the rules governing Civil Service, and the special trust placed in public servants.

Benefits
Information on benefits afforded by membership in the California Public Employees’
Retirement System can be found on the California Department of Human
Resources (CalHR) Salary and Benefits website at www.calhr.ca.gov/employees/pages/salary-and-benefits.aspx.

Information regarding Merit System Principles provided to public employees by the
State Civil Service Act can be found on the CalHR website at https://www.calhr.ca.gov/Training/Pages/performance-management-merit- system-principles.aspx.

Additional benefit information can be found on the CalHR California State Civil
Service Employee Benefits Summary website at https://www.calhr.ca.gov/Pages/California-State-Civil-Service-Employee-Benefits-
Summary.aspx. This webpage is intended to provide general information.

*All hires at CIRM are Exempt from civil service and considered Excluded for the purposes of collective bargaining.

Job Type: Full-time

Pay: $145,491.00 - $228,273.00 per year

Benefits:

• 401(k)
• Dental insurance
• Employee assistance program
• Flexible schedule
• Flexible spending account
• Health insurance
• Life insurance
• Paid time off
• Retirement plan
• Vision insurance

Schedule:

• 8 hour shift

Ability to commute/relocate:

• San Francisco, CA 94080: Reliably commute or planning to relocate before starting work (Required)

Application Question(s):

• Years of Experience with biologic/drug development, Clinical & regulatory development, pharmaceutical

/biotechnology industry, and/or biomedical clinical research?

• Years of experience with clinical project management and regulatory filings or interactions (FDA, pre-IND, and IND filings)?
• Do you possess a specialty in one of the following therapeutic areas: Therapeutic areas - neurology, ophthalmology, hematology/oncology or organ systems (cardiology, vascular, liver, or renal)?
• Years of experience with clinical development of cell and gene therapy?

Education:

• Doctorate (Required)

Work Location: One location

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