Job description
ABOUT US
Sorrento Therapeutics Inc. is a fast growing, clinical stage, antibody-centric, biopharmaceutical company developing new therapies to turn malignant cancers into manageable and possibly curable diseases. Sorrento's multimodal multipronged approach to fighting cancer is made possible by its' extensive immuno-oncology platforms, including key assets such as fully human antibodies ("G-MAB™ library"), clinical stage immuno-cellular therapies ("CAR-T"), intracellular targeting antibodies ("iTAbs"), antibody-drug conjugates ("ADC"), and clinical stage oncolytic virus ("Sephrevir®").
We attract smart people who play well with others. We're small enough for your ideas to make a big impact, and large enough to offer you opportunities to grow professionally at any stage of your career.
If you’re a quick learner, enjoy working in the biotech industry, and share our mission of providing ground-breaking impact to medicine, each other, and our patients, Sorrento Therapeutics is the place for you!
Sorrento Therapeutics, Inc. is a federal government contractor and, in compliance with its obligations under current federal regulations, Sorrento requires all employees, including newly hired employees, to present proof of vaccination against COVID-19, unless the employee is legally entitled to an accommodation. For further information, please refer to the Safer Federal Workforce Task Force’s September 24, 2021 Guidance for Federal Contractors and Subcontractors, available at: https://www.saferfederalworkforce.gov/contractors/.
WHAT WE ARE LOOKING FOR:
Target Salary Range ($64,480-$67,000)
Sorrento Therapeutics (“Sorrento”) is seeking an experienced Research Associate who will work in the area of mRNA production. Responsible for mRNA production as well as for process development. This will include, but not limited to, mRNA production process development, process scale-up, process execution to make material for preclinical studies. This individual will join a dynamic, rapidly growing, and highly collaborative team that is driving the mRNA process development and manufacturing for multiple mRNA platforms and drug products.
WHAT YOU’LL DO:
- Support the development of in-house mRNA production capabilities, with an emphasis on establishing a scalable/transferable process for producing high-purity material
- Execute experimental plans for screening, optimization, and scale-up efforts for mRNA synthesis, and purification
- Develop and optimize enzyme catalyzed in vitro transcription (IVT) for mRNA production
- Implement scalable mRNA purification by using AKTA and HPLC
- Develop and run analytical assays including HPLC, Fragment Analyzer, qPCR, LAL, ELISA etc.
- Manufacture mRNA for formulation and other platform teams
- Coordinate with multiple scientists for scheduling and execution of experiments
- Analyze, record, and maintain data on results and communicate results to appropriate personnel accurately documenting findings within electronic laboratory notebook and computer files in a timely manner.
- Prepares reagents, chemical solutions and biological samples for laboratory procedures.
- Participates and contributes in group and project meetings as required.
- Works in accordance with safety guidelines.
- Performs other duties as assigned.
EDUCATION AND QUALIFICATIONS:
- Bachelor’s Degree in Molecular Biology or related disciplines
- Experience with AKTA, HPLC, TFF and other standard analytical techniques highly preferred
- Technical understanding and experience in biopharmaceutical process development including protein or RNA synthesis, and purification is required
- Operate specialized laboratory equipment and computers as appropriate to the individual laboratory (including instrument maintenance and calibration).
- Good analytical skills.
- Good inter-personal skills and communication skills (both written and oral).
- Proficient at writing and oral presentations.
- Proficient in the use of standard desktop computer software programs.
- Effective project and time management skills.
- Team player capable of operating in a dynamic matrix environment.
YOUR REWARD:
- Support scientists who are on the leading edge of immunotherapies for the treatment of cancer.
- Earn a competitive salary that allows you to focus your attention on your passion.
- A comprehensive benefits package including: medical, dental, vision, life and disability insurance, matching 401k, company paid holidays, and Flexible PTO, plus stock options.
If this sounds like the right career to fit your personality and interests, please apply, we’re looking forward to meeting you!
Principals only. Recruiters, please don't contact this job poster.
Sorrento Therapeutics, Inc. is an Equal Opportunity Employer
Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities
The contractor will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, or (c) consistent with the contractor’s legal duty to furnish information. 41 CFR 60-1.35(c)
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